Dermoelectroporation is a non-invasive method developed by Mattioli Engineering Research Labs for delivering drugs into the body. It works by creating channels in the skin using controlled electrical pulses, allowing ionic drug solutions to penetrate deeply. This technology enhances skin permeability, enabling the transdermal delivery of drugs similar to traditional iontophoresis. Importantly, it does not alter the properties of the drug solution being delivered.

DEP is an FDA-certified medical device endorsed for needle-free administration. It can efficiently transport high-molecular-weight growth factors and peptides deep into the skin's dermal layer. During treatment, personalized solutions are introduced to address various skin concerns.

As a result of electronic stimulation of facial muscles, the majority of clients can observe and feel the tightening and firming of their facial skin. The incorporation of growth factors leads to increased skin radiance, an improved skin texture, and reduced pore visibility. Monthly DEP facials accelerate the process of skin rejuvenation, resulting in a more youthful and radiant complexion.

The TransdermIonto System is a powered drug delivery system designed for the localized administration of ionic drug solutions into the body for medical purposes. It serves as a needle-free alternative and must be administered by a licensed healthcare professional using approved substances.

The Transderm Ionto System facilitates the transdermal delivery of ionic drug solutions into the body, enabling the active ingredients to penetrate the dermis without the need for injections or syringes. The Ultrapeel Transderm Ionto System combines conventional microdermabrasion with Dermoelectroporation, offering the advantages of transdermal drug delivery without the potential side effects associated with traditional techniques.

This system employs microdermabrasion to gently exfoliate the stratum corneum, ensuring consistent results. Additionally, it utilizes Dermoelectroporation, which allows the active substances to enter the dermis through low-energy electrical pulses, facilitating the delivery of ionic drug solutions into the body.

When combined with microdermabrasion, Dermoelectroporation significantly enhances the transdermal delivery rate, achieving a level of absorption five times greater than that of topical applications.

As per the FDA clearance, the Transderm Ionto System is a powered drug delivery system designed for the localized administration of ionic drug solutions into the body for medical purposes, offering an alternative to injections.

The TransdermIonto System is acknowledged for its ability to transdermally transport ionic drug solutions to the muscle membranes.

The Transderm Ionto System stands alone as the sole FDA-cleared system for medical applications, serving as a recognized alternative to injections. It possesses the capacity to transdermally transport both micro- and macro-molecules, ensuring the complete delivery of the ionic drug solution without any electrolysis and maintaining consistent pH levels to prevent patient irritation.

This system enhances the transdermal delivery rate through the combined action of microdermabrasion and Dermoelectroporation, guaranteeing dose reproducibility through preliminary microdermabrasion. Additionally, the built-in vibration feature minimizes the perception of electrical pulses for the patient. Importantly, the Transderm Ionto System is a non-invasive treatment option.